… Below we present the case of a 7-month-old male presenting with a large posterior neck
mass that was diagnosed as spindle cell rhabdomyosarcoma. Karyotype evaluation revealed at(…

… RMS with translocations of the SRF gene. According to the … this review we found three cases
with a diagnosis of spindle cell/sclerosing rhabdomyosarcoma, one of them does not report …

… translocations t(2; 13) or t(1; 13) are present in most cases. Typical … Our literature review
(Table 1) identified 122 cases of … head and neck area, although pediatric spindle cell RMS arises …

… Extensive literature review of the pathyophysiology of these … Figure 2- Shows nests of solid
spherical to spindle cells … is the result of unique reciprocal 1,3 translocation between (2,13,)(35…

… [ 1 ] Most of the RMSs are located in the head and neck, … of solid variant of ARMS with
spindle cells and epithelial … the tumor cell nucleus with the FKHR translocation had one …

… was consistent with a spindle cell RMS with t(8;11)(q13;p15) TEAD1-NCOA2 translocation.
A … were head and neck locations (29%) (orbital, base of tongue, neck) with only one reported …

… (ERMS) includes botryoid and spindle cell variants, which collectively possess no … case,
we were unable to detect a FOXO1a translocation by FISH. A complicating factor is a report by …

… We present a case of diaphragmatic spindle cell embryonal … The t(2;13) translocation results
in fusion of part of the PAX3 … (ie, the head and neck, but not the parameningeal area and the …

… About 35% of RMS arises in the head and neck. According to … : (a) botryoid and spindle cell
RMS (both less common variants of … disease and variant-translocation-positive alveolar RMS (…

… chromosomal translocations are helpful for diagnosis (eg, more than 80% of patients with
alveolar rhabdomyosarcoma have one of two types of chromosome translocations). Citation20 …