… vascular inflammation. Importantly, by using this 3D model we identified RhoA, Rac1,
and N-cadherin as important regulators in mural–endothelial cell-mediated vascular barrier …

… vascular inflammation. Importantly, by using this 3D model we identified RhoA, Rac1,
and N-cadherin as important regulators in mural–endothelial cell-mediated vascular barrier …

… , we developed an N-cadherin biomimetic platform (N-cad-… demonstrate that N-cadherin
activates both Rac1 and RhoA via … S3 shows protein interaction scores from the N-cadherin MS …

… Rho family GTPases, Rac-1, Cdc42, and RhoA. In epithelial … of an N-cadherin-Fc chimera
(extracellular domain of N-cadherin … We aimed to engineer a truly three-dimensional model of …

… that drive dynamic behavior in vascular endothelial cells is not … Our theoretical model reveals
that active cell tension can … a balance and crosstalk between RhoA and Rac1 signaling is …

… localization specifically on N-cadherin biomimetic surfaces. In … both Rac1 and RhoA
downstream of N-cadherin adhesions. … of Rac1 at mature AJs is a pivotal mechanism for balancing …

… Theneuronal cadherin (N‐cadherin) could also mediate the interactions. At this stage,
cells … Cancer cells promote activation of RAC1, RHOA–RHO-associated protein kinase (ROCK) …

… Several family members have been identified in the vascular … of vascular permeability and
angiogenesis, and N-cadherin … of resulting spheroids in three-dimensional gels. This approach …

… vascular 81 tissue. The best studied are endothelial VE-cadherin which plays an essential
role in regulation 82 of vascular permeability and angiogenesis, and N-cadherin … N-cadherin …

… is the increased expression of N-cadherin, which is typically … In particular, RAC1 and CDC42
activate actin polymerization … were cultured in three-dimensional geometries, including PA …