… hypoxia has on the ability of pancreatic cancer cells to invade and metastasize. Hypoxia
activates signaling pathways in both cell-… -invasive interactions between cancer and stromal cells…

… of hypoxia and HGF-driven cell invasiveness involves other … We report here that multiple
pathways, including the mitogen-… ) pathways, mediate the synergistic invasiveness triggered by …

… of pancreatic cancer (PC)) interact with cancer cells to facilitate PC growth. A candidate … that
targeting of a specific pathway such as the HGF-c-MET pathway, by inhibiting its active ligand…

… Fifth, hypoxia-driven up-regulation of c-Met seems to … the activation of paracrine hepatocyte
growth factor/c-Met … factor and the Met system as a mediator of tumor-stromal interactions. …

… affect pancreatic cancer cell invasion and EMT by interfering with tumor‑stromal interaction
under hypoxic … the hepatocyte growth factor (HGF)/c-Met/survivin pathway, which is negatively …

… , our results illuminate tumor–stromal interactions, which drive … invasion assay using coculture
of Panc10.05 and hCAF cells … of the hepatocyte growth factor/c-MET pathway in pancreatic …

… to binding of its ligand, hepatocyte growth factor (HGF), also … in the development of
tumorigenesis, invasion, metastasis and … Hypoxia-induced tumor cell invasion is dependent upon …

… HGF and tumor stromal cells Solid tumors are not just a mass of neoplastic … the invasiveness
of pancreatic cancer cells through the hepatocyte growth factor/ c-Met pathway. Int. J…

… that there is an important interaction between the stromal … in the growth, invasion and
metastasis of pancreatic cancer. The … stromal cells in PDA resulted in an immune-mediated …

… tumor–stromal interaction between PSCs in hypoxia and in normoxia, … Hepatocyte growth
factor (HGF), a well-known growth factor, … cells within pancreatic cancer existed in hypoxia, and …