α-Glucosidase and 15-Lipoxygenase Inhibitory Activities of Phytochemicals from Calophyllum symingtonianum
A phytochemical investigation of the crude extracts of the bark and leaves of Calophyllum
symingtonianum has resulted in the isolation of inophyllum D, inophyllum H, calanone,
isocordato-oblongic acid, amentoflavone, carpachromene and lupenone. Their chemical
structures were elucidated and confirmed by spectroscopic analysis. All flavonoids and
coumarins showed significant α-glucosidase inhibitory activity, while amentoflavone gave a
positive result against 15-lipoxygenase inhibition.
symingtonianum has resulted in the isolation of inophyllum D, inophyllum H, calanone,
isocordato-oblongic acid, amentoflavone, carpachromene and lupenone. Their chemical
structures were elucidated and confirmed by spectroscopic analysis. All flavonoids and
coumarins showed significant α-glucosidase inhibitory activity, while amentoflavone gave a
positive result against 15-lipoxygenase inhibition.
α-Glucosidase and 15-lipoxygenase inhibitory activities of phytochemicals from Calophyllum symingtoni.
A phytochemical investigation of the crude extracts of the bark and leaves of Calophyllum
symingtonianum has resulted in the isolation of inophyllum D, inophyllum H, calanone,
isocordato-oblongic acid, amentoflavone, carpachromene and lupenone. Their chemical
structures were elucidated and confirmed by spectroscopic analysis. All flavonoids and
coumarins showed significant α-glucosidase inhibitory activity, while amentoflavone gave a
positive result against 15-lipoxygenase inhibition.
symingtonianum has resulted in the isolation of inophyllum D, inophyllum H, calanone,
isocordato-oblongic acid, amentoflavone, carpachromene and lupenone. Their chemical
structures were elucidated and confirmed by spectroscopic analysis. All flavonoids and
coumarins showed significant α-glucosidase inhibitory activity, while amentoflavone gave a
positive result against 15-lipoxygenase inhibition.
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