κ-Opioid receptors in the substantia nigra pars reticulata mediate the U-50,488-induced locomotor activity of preweanling rats
RL Collins, AR Zavala, A Nazarian… - Developmental Brain …, 2000 - Elsevier
The purpose of the present study was to determine the neuroanatomical location where κ-
opioid receptor stimulation induces locomotor activity in the preweanling rat. To confirm that
the U-50,488-induced locomotor activity of preweanling rats is mediated by κ-opioid
receptors, 18-day-old rats were initially injected with vehicle or the κ-opioid receptor agonist
U-50,488 (5 mg/kg, sc) followed, 15 min later, by an injection of the κ-opioid receptor
antagonist nor-binaltorphimine (nor-BNI; 0, 2, 4, 8, or 12 mg/kg, sc). In subsequent …
opioid receptor stimulation induces locomotor activity in the preweanling rat. To confirm that
the U-50,488-induced locomotor activity of preweanling rats is mediated by κ-opioid
receptors, 18-day-old rats were initially injected with vehicle or the κ-opioid receptor agonist
U-50,488 (5 mg/kg, sc) followed, 15 min later, by an injection of the κ-opioid receptor
antagonist nor-binaltorphimine (nor-BNI; 0, 2, 4, 8, or 12 mg/kg, sc). In subsequent …
以上显示的是最相近的搜索结果。 查看全部搜索结果