Apoptosis-inducing effect of erlotinib is potentiated by 3,3′-diindolylmethane in vitro and in vivo using an orthotopic model of pancreatic cancer

S Ali, S Banerjee, A Ahmad, BF El-Rayes… - Molecular cancer …, 2008 - AACR
… Results of this study clearly show that the benefit of combining erlotinib and B-DIM will be
limited to cells that have EGFR pathway activation probably driven by NF-κB activation. …

Erlotinib or best supportive care for third-line treatment of advanced non-small-cell lung cancer: a real-world cost-effectiveness analysis

I Cromwell, K van der Hoek, SCM Taylor, B Melosky… - Lung Cancer, 2012 - Elsevier
… Patients in the treatment group received erlotinib according to BCCA protocols: erlotinib 150
… at which time erlotinib is discontinued [5]. The most common adverse effect of erlotinib is a …

Erlotinib: a pharmacoeconomic review of its use in advanced non-small cell lung cancer

KA Lyseng-Williamson - Pharmacoeconomics, 2010 - Springer
… patients receiving erlotinib 150 mg/day than in those receiving placebo. Erlotinib is generally
… data suggests that second- or third-line erlotinib 150mg/day is a cost-saving option relative …

A phase II trial of erlotinib in patients with recurrent malignant gliomas and nonprogressive glioblastoma multiforme postradiation therapy

JJ Raizer, LE Abrey, AB Lassman, SM Chang… - Neuro …, 2010 - academic.oup.com
… In conclusion, single-agent erlotinib has minimal activity in the settings studied and additional
research should probably focus on multi-agent strategies, multi-targeting agents that may …

[HTML][HTML] Comparative efficacy and safety of erlotinib in non-small cell lung cancer (NSCLC) of squamous cell and adenocarcinoma histology in the phase III NCIC CTG …

S Wojtowicz-Praga, L Leon - Annals of Oncology, 2012 - Elsevier
… Analyses of data from two large pivotal trials associated erlotinib treatment with significant
survival benefit in both SC and AD histology subgroups, supporting its efficacy in pts with SC …

Erlotinib in the treatment of advanced non-small cell lung cancer: an update for clinicians

Y Wang, G Schmid-Bindert… - Therapeutic advances in …, 2012 - journals.sagepub.com
erlotinib 150 mg orally on days 2–15 every 3 weeks for four cycles followed by erlotinib 150
mg orally until PD occurred (CT + erlotinib). … (CT + erlotinib and erlotinib alone, respectively). …

Cost-effectiveness of three strategies for second-line erlotinib initiation in nonsmall-cell lung cancer: the ERMETIC study part 3

I Borget, J Cadranel, JP Pignon, E Quoix… - European …, 2012 - Eur Respiratory Soc
study was to compare the incremental cost-effectiveness ratios of strategies for second-line
erlotinib … (nonsmoking females with adenocarcinoma received erlotinib; all other patients …

Effectiveness and cost-effectiveness of erlotinib versus gefitinib in first-line treatment of epidermal growth factor receptor-activating mutation-positive non-small-cell …

VWY Lee, B Schwander, VHF Lee - Hong Kong Medical Journal, 2014 - hub.hku.hk
… 隨機對照試 驗中,其中一個使用 erlotinib( OPTIMAL),另三個使用 … erlotinib 與gefitinib的無惡化
生存期的危險系數,發現erlotinib在… 把erlotinib與 gefitinib比較,成本效益評估模型顯示erlotinib的無…

Colorectal cancer growth retardation through induction of apoptosis, using an optimized synergistic cocktail of axitinib, erlotinib, and dasatinib

RH Berndsen, N Swier, JR van Beijnum… - Cancers, 2019 - mdpi.com
… ), erlotinib (20 μM), and dasatinib (0.2 μM) [20]. In this study, the activity of axitinib, erlotinib,
and … Exposure of CRC cells to 2- and 3-drug combinations of axitinib, erlotinib, and dasatinib …

[HTML][HTML] Quality of life (QoL) analyses from OPTIMAL (CTONG-0802), a phase III, randomised, open-label study of first-line erlotinib versus chemotherapy in patients …

G Chen, J Feng, C Zhou, YL Wu, XQ Liu, C Wang… - Annals of …, 2013 - Elsevier
… PFS benefit from erlotinib than from chemotherapy, making erlotinib the … In conclusion, our
study demonstrates that erlotinib … Our study provides further support for the use of erlotinib in …