A focused salivary gland infection with attenuated MCMV: an animal model with prevention of pathology associated with systemic MCMV infection
MJ Pilgrim, L Kasman, J Grewal, ME Bruorton… - … and molecular pathology, 2007 - Elsevier
While the salivary gland has been recognized as an important effector site of the common
mucosal immune system, a useful model for studying anti-viral salivary gland immune
responses in vivo and for exploring the role of the salivary gland within the common mucosal
system has been lacking. Murine cytomegalovirus (MCMV) is a beta-herpesvirus that
displays a strong tropism for the salivary gland and produces significant morbidity in
susceptible mice when introduced by intraperitoneal (ip) inoculation. This study tested the …
mucosal immune system, a useful model for studying anti-viral salivary gland immune
responses in vivo and for exploring the role of the salivary gland within the common mucosal
system has been lacking. Murine cytomegalovirus (MCMV) is a beta-herpesvirus that
displays a strong tropism for the salivary gland and produces significant morbidity in
susceptible mice when introduced by intraperitoneal (ip) inoculation. This study tested the …
以上显示的是最相近的搜索结果。 查看全部搜索结果