Entrepreneurship is often thought of as the act of commercializing an innovation. In modern open economies, entrepreneurship is one of the key aspects for economic growth. Teaching and learning entrepreneurship is therefore of importance and schools, colleges and universities can play an important role by including entrepreneurship and innovation in their curricula. The Berkeley Method of Entrepreneurship is a holistic and student-centered teaching and learning approach that is hypothesized to enable engineers to be more entrepreneurial. It encompasses three main elements; networks, mindset and frameworks. Networks and Framewoks are covered in most entrepreneurial curricula, whereas only few curricula explicitly include the mindset perspective. The Berkeley Method of Entrepreneurship is based on the hypothesis that the mindset of an entrepreneur can be characterized by a distinct set of behavioral patterns, and that an inductive game-based teaching approach is a successful vehicle for introducing and re-enforcing these. The game-based teaching approach lets the students explore his/her current mindset and compare it with that of entrepreneurs. The paper presents two of the hypothesis behind the Berkeley Method of Entrepreneurship; the set of behavioral patterns, and the game based teaching approach. The paper outlines the concepts behind this novel teaching approach as well as future research.