In recent years, kinship care has become a major contributor to the delivery of out-of-home care services in most Western jurisdictions. Over time, statutory kinship care has been modelled on the more established foster-care system. Yet the particular nature of kinship care differs from stranger care arrangements in important ways. This often results in kinship carers and their children being disadvantaged and poorly responded to within foster-care-dominated systems. This article discusses the development of a kinship care practice framework that responds to the particular needs of kith and kin carers and the children they care for within statutory systems of care, and which also takes into account the particular complexities of kinship care practice. Recognising that kinship carers come to the role at different ages, from siblings, aunts and uncles, as well as grandparents, the framework takes a life course approach that responds to both the generic and age-specific needs of the carer. Life course issues and challenges are considered across four domains supporting practice that is: child-centred; relationship-supportive; family and culturally responsive; and system-focused.