A modular electrochemical peptide-based sensor for antibody detection

M Puiu, A Idili, D Moscone, F Ricci… - Chemical Communications, 2014 - pubs.rsc.org
Chemical Communications, 2014pubs.rsc.org
We report a modular electrochemical peptide-based sensor targeting the anti-deamidated
gliadin peptide (DGP) antibody. A recognition peptide, here DGP, is grafted onto a
supporting peptide bearing a redox label. The fabricated peptide-based sensor supports the
detection of the target antibody (anti-DGP antibody) in the nanomolar range.
We report a modular electrochemical peptide-based sensor targeting the anti-deamidated gliadin peptide (DGP) antibody. A recognition peptide, here DGP, is grafted onto a supporting peptide bearing a redox label. The fabricated peptide-based sensor supports the detection of the target antibody (anti-DGP antibody) in the nanomolar range.
The Royal Society of Chemistry
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