This pilot study investigated whether computer‐based learning package followed by practical instruction and traditional classroom methods were comparable in developing knowledge and skills in basic life support with automated external defibrillator. Eighty‐three mental health care professionals were allocated to one of two groups. Twenty‐eight completed an e‐learning package, and the remaining 55 received delivery of content in a classroom. Using standardized assessment methods, comparisons of participant knowledge gain and performance in resuscitation were made. Significant increases in knowledge followed training. No differences were found with basic resuscitation skills or in the time taken to the first shock; however, both groups were inaccurate with electrode pad placement. E‐learners performed slightly better in 21 of the 30 observed skills. Overall group performance did not differ suggesting computer‐based education has the potential to prepare learners in resuscitation knowledge and skills to comparable levels of classroom courses.