BACKGROUND: After resuscitation from hemorrhagic shock, intestinal microvessels
constrict leading to impairment of blood flow. This occurs despite restoration and
maintenance of central hemodynamics. Our recent studies have demonstrated that topical
and continuous exposure of the gut microvasculature to a clinical solution (Delflex;
Fresenius Medical Care), as a technique of direct peritoneal resuscitation (DPR), reverses
the postresuscitation vasoconstriction and hypoperfusion to a sustained dilation and …