A randomized, placebo-controlled study of pregabalin for postoperative pain intensity after laparoscopic cholecystectomy

F Balaban, S Yağar, A Özgök, M Koç… - Journal of clinical …, 2012 - Elsevier
STUDY OBJECTIVE: To determine the efficacy of two different doses (150 mg and 300 mg)
of preoperative pregabalin on pain relief and total opioid consumption after laparoscopic
cholecystectomy. DESIGN: Prospective, randomized, placebo-controlled, double-blinded
study. SETTING: Training and research hospital. PATIENTS: 90 adult, ASA physical status 1
and 2 patients. INTERVENTIONS: Patients were randomly assigned to three groups to
receive orally one hour before surgery, a placebo (Group 1), pregabalin 150 mg (Group 2) …
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