Data on bovine and human tuberculosis in Maiduguri for five years (2005-2009) were collated and analyzed. The results did show that more cases of bovine tuberculosis occurred in 2005 (P< 0.001) compared with 2007, 2008 and 2009. There was no significant difference in the number of cases (P> 0.05) between 2005 and 2006. The number of cases of bovine tuberculosis was significantly different (P< 0.001) when 2006 was compared with 2008 and 2009. For human tuberculosis, the number of cases for the five years (2005-2009) did not differ significantly (P> 0.05). On the bases of sex for humans, in year 2008, there was significant number of cases in males compared to females and the difference was significant (P< 0.05). Data on age of persons showed significant difference (P< 0.05) between the age brackets 15-30 and 31-45 years. Our data revealed that pulmonary tuberculosis occurred significantly higher (P< 0.001) when compared with cases of extra pulmonary tuberculosis. In conclusion, our data has shown that both human and bovine tuberculosis still pose a threat to the health management in Maiduguri. We therefore recommend that appropriate preventive and control measures be instituted as an intervention programme.