The production of β-lactamases is a prevalent mechanism that poses serious pressure on
the control of bacterial resistance. Furthermore, the unavoidable and alarming increase in
the transmission of bacteria producing extended-spectrum β-lactamases complicates
treatment alternatives with existing drugs and/or approaches. Class D β-lactamases,
designated as OXA enzymes, are characterized by their activity specifically towards
oxacillins. They are widely distributed among the ESKAPE bugs that are associated with …

The production of beta-lactamases is a prevalent mechanism that poses serious pressure on
the control of bacterial resistance. Furthermore, the unavoidable and alarming increase in
the transmission of bacteria producing extended-spectrum beta-lactamases complicates
treatment alternatives with existing drugs and/or approaches. Class D beta-lactamases,
designated as OXA enzymes, are characterized by their activity specifically towards
oxacillins. They are widely distributed among the ESKAPE bugs that are associated with …