A semi-empirical model to optimize continuous-flow hyperpolarized 129Xe production under practical cryogenic-accumulation conditions
Continuous-flow spin exchange optical pumping (SEOP) with cryogenic accumulation is a
powerful technique to generate multiple, large volumes of hyperpolarized (HP) 129 Xe in
rapid succession. It enables a range of studies, from dark matter tracking to preclinical and
clinical MRI. Multiple analytical models based on first principles atomic physics and device-
specific design features have been proposed for individual processes within HP 129 Xe
production. However, the modeling efforts have not yet integrated all the steps involved in …
powerful technique to generate multiple, large volumes of hyperpolarized (HP) 129 Xe in
rapid succession. It enables a range of studies, from dark matter tracking to preclinical and
clinical MRI. Multiple analytical models based on first principles atomic physics and device-
specific design features have been proposed for individual processes within HP 129 Xe
production. However, the modeling efforts have not yet integrated all the steps involved in …
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