A single-dose live-attenuated vaccine prevents Zika virus pregnancy transmission and testis damage
… of sexual transmission. Here we demonstrate that live-attenuated Zika virus vaccine candidates
… in the 3′ untranslated region of the Zika virus genome (ZIKV-3′UTR-LAV) prevent viral …
… in the 3′ untranslated region of the Zika virus genome (ZIKV-3′UTR-LAV) prevent viral …
A single-dose plasmid-launched live-attenuated Zika vaccine induces protective immunity
… To achieve this goal, we have developed a single-dose DNA-launched LAV that … single-dose
live-attenuated vaccine prevents Zika virus pregnancy transmission and testis damage…
live-attenuated vaccine prevents Zika virus pregnancy transmission and testis damage…
A single-dose live-attenuated vaccine prevents Zika virus pregnancy transmission and testis damage
BW Jagger, J Richner, MS Diamond - 2017 - digitalcommons.wustl.edu
… of sexual transmission. Here we demonstrate that live-attenuated Zika virus vaccine candidates
… in the 3′ untranslated region of the Zika virus genome (ZIKV-3′UTR-LAV) prevent viral …
… in the 3′ untranslated region of the Zika virus genome (ZIKV-3′UTR-LAV) prevent viral …
A single-dose live-attenuated Zika virus vaccine with controlled infection rounds that protects against vertical transmission
… use in pregnant women is critically needed. Toward this goal, we have developed a single-dose
live-attenuated vaccine … The vaccine contains a 9-amino-acid deletion in the viral capsid …
live-attenuated vaccine … The vaccine contains a 9-amino-acid deletion in the viral capsid …
A systematic approach to the development of a safe live attenuated Zika vaccine
… Zika virus (ZIKV) is a flavivirus that can cause congenital … (LAV) would be advantageous,
as a single dose of YF17D … (brain) or sexual transmission of the virus (testes and kidney) 17 . …
as a single dose of YF17D … (brain) or sexual transmission of the virus (testes and kidney) 17 . …
Live vaccine infection burden elicits adaptive humoral and cellular immunity required to prevent Zika virus infection
… yellow fever live attenuated vaccine (YF17D) … prevent infection of certain organs such as
the testes, highlighting their possible necessity in preventing silent transmission from vaccinated …
the testes, highlighting their possible necessity in preventing silent transmission from vaccinated …
Zika virus—an update on the current efforts for vaccine development
VAS Lunardelli, JDS Apostolico… - Human Vaccines & …, 2021 - Taylor & Francis
… in mice and rhesus macaques, also preventing pregnancy transmission and testis damage
in mice. Citation29 Similarly, a single-dose of plasmid-launched live-attenuated ZIKV …
in mice. Citation29 Similarly, a single-dose of plasmid-launched live-attenuated ZIKV …
Rational development of live-attenuated Zika virus vaccines
A Adam, C Lee, T Wang - Pathogens, 2023 - mdpi.com
… ZIKV challenges and prevent maternal transmission to the fetus [63]… A single dose of this
attenuated virus was able to trigger … from viral transmission during pregnancy and testis damage …
attenuated virus was able to trigger … from viral transmission during pregnancy and testis damage …
Development of a chimeric Zika vaccine using a licensed live-attenuated flavivirus vaccine as backbone
XF Li, HL Dong, HJ Wang, XY Huang, YF Qiu… - Nature …, 2018 - nature.com
… Zika virus (ZIKV) is a mosquito-borne virus belonging to the … Viral RNA was barely
detectable in the spleens and testis of … In our study, a single dose of ChinZIKV can induce high …
detectable in the spleens and testis of … In our study, a single dose of ChinZIKV can induce high …
Protective efficacy of nucleic acid vaccines against transmission of zika virus during pregnancy in mice
… who received the live-attenuated tetravalent Dengvaxia vaccine and were subsequently …
One caveat to our studies in mice and their potential to prevent vertical transmission of ZIKV …
One caveat to our studies in mice and their potential to prevent vertical transmission of ZIKV …