A smart DNA–gold nanoparticle probe for detecting single-base changes on the platform of a quartz crystal microbalance
A design of DNA–gold nanoparticle probe-fueled DNA strand displacements for detecting
single-base changes on the platform of a quartz crystal microbalance with random
sequences was developed. After optimizing and testing the detection system, it has been
successfully applied to detect mutation of a realistic sequence associated with human
cancer, thereby indicating that this method has potential applicability in general.
single-base changes on the platform of a quartz crystal microbalance with random
sequences was developed. After optimizing and testing the detection system, it has been
successfully applied to detect mutation of a realistic sequence associated with human
cancer, thereby indicating that this method has potential applicability in general.
A design of DNA–gold nanoparticle probe-fueled DNA strand displacements for detecting single-base changes on the platform of a quartz crystal microbalance with random sequences was developed. After optimizing and testing the detection system, it has been successfully applied to detect mutation of a realistic sequence associated with human cancer, thereby indicating that this method has potential applicability in general.
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