A study of aanat and asmt expression in the three-spined stickleback eye and skin: Not only “on the way to melatonin”
K Pomianowski, M Gozdowska, A Burzyński… - … and Physiology Part A …, 2020 - Elsevier
Melatonin synthesis is controlled by aralkylamine N-acetyltransferase (AANAT: EC 2.3. 1.87)
acetylating serotonin (5-hydroxytryptamine; 5-HT) to N-acetylserotonin (NAS), and N-
acetylserotonin O-methyltransferase (ASMT: EC 2.1. 1.4) methylating NAS to melatonin (Mel;
N-acetyl-5-methoxytryptamine). We examined the levels of expression of the aanat and asmt
genes, Mel concentrations as well as AANAT isozyme activity in the eyeball (with retina) and
skin of the three-spined stickleback (Gasterosteus aculeatus), at noon and midnight. We …
acetylating serotonin (5-hydroxytryptamine; 5-HT) to N-acetylserotonin (NAS), and N-
acetylserotonin O-methyltransferase (ASMT: EC 2.1. 1.4) methylating NAS to melatonin (Mel;
N-acetyl-5-methoxytryptamine). We examined the levels of expression of the aanat and asmt
genes, Mel concentrations as well as AANAT isozyme activity in the eyeball (with retina) and
skin of the three-spined stickleback (Gasterosteus aculeatus), at noon and midnight. We …
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