UAVs have been contributing substantially to multi-disciplinary research and around 70% of the articles have been published in just about the last five years, with an exponential increase. Primarily, while exploring the literature from the scientific databases for various aspects within the autonomous UAV path planning, such as type and configuration of UAVs, the complexity of their environments or workspaces, choices of path generating algorithms, nature of solutions and efficacy of the generated paths, necessitates an increased number of search keywords as a prerequisite. However, the addition of more and more keywords might as well curtail some conducive and worthwhile search results in the same pursuit. This article presents a Systematic Literature Review (SLR) for 20 useful parameters, organized into six distinct categories that researchers and industry practitioners usually consider. In this work, Web of Science (WOS) was selected to search the primary studies based on three keywords: “Autonomous” + “Path Planning” + “UAV” and following the exclusion and inclusion criteria defined within the SLR methodology, 90 primary studies were considered. Through literature synthesis, a unique perspective to see through the literature is established in terms of characteristic research sectors for UAVs. Moreover, open research challenges from recent studies and state-of-the-art contributions to address them were highlighted. It was also discovered that the autonomy of UAVs and the extent of their mission complexities go hand-in-hand, and the benchmark to define a fully autonomous UAV is an arbitral goal yet to be achieved. To further this quest, the study cites two key models to measure a drone’s autonomy and offers a novel complexity matrix to measure the extent of a drone’s autonomy. Additionally, since preliminary-level researchers often look for technical means to assess their ideas, the technologies used in academic research are also tabulated with references.