A systematic review of the literature on the effects of dexamethasone on the brain from in vivo human-based studies: implications for physiological brain imaging of …

C Kotsarini, PD Griffiths, ID Wilkinson, N Hoggard - Neurosurgery, 2010 - journals.lww.com
BACKGROUND: Among glucocorticoids, dexamethasone is most widely used for treatment
of cerebral edema because of its long biological half-life and its low mineralocorticoid
activity (sodium retaining). OBJECTIVE: A systematic review of the literature on the effects of
dexamethasone on the brain from in vivo studies in humans. METHODS: A MEDLINE
database search (via the PubMed interface) and an EMBASE database search (via the
Dialog interface) of the past 35 years was performed. Every article relating to human use …
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