A unique adolescent response to reward prediction errors

JR Cohen, RF Asarnow, FW Sabb, RM Bilder… - Nature …, 2010 - nature.com
JR Cohen, RF Asarnow, FW Sabb, RM Bilder, SY Bookheimer, BJ Knowlton, RA Poldrack
Nature neuroscience, 2010nature.com
Previous work has shown that human adolescents may be hypersensitive to rewards, but it
is not known which aspect of reward processing is responsible for this. We separated
decision value and prediction error signals and found that neural prediction error signals in
the striatum peaked in adolescence, whereas neural decision value signals varied
depending on how value was modeled. This suggests that heightened dopaminergic
prediction error responsivity contributes to adolescent reward seeking.
Abstract
Previous work has shown that human adolescents may be hypersensitive to rewards, but it is not known which aspect of reward processing is responsible for this. We separated decision value and prediction error signals and found that neural prediction error signals in the striatum peaked in adolescence, whereas neural decision value signals varied depending on how value was modeled. This suggests that heightened dopaminergic prediction error responsivity contributes to adolescent reward seeking.
nature.com
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