Traditional odor control methods are limitative technically and economically for the abatement of odor from pesticide factory due to its toxicity and complicated composition. Non-thermal plasma (NTP) methods, typically characterized by high removal efficiency, energy yields and good economy, offer possible alternative solutions. This paper provides laboratory scale experimental data on the removal of simulated odors from pesticide factory with various humidity (0–0.8vol%) and oxygen contents (0–21%) by a dielectric barrier discharge (DBD) reactor. Peak voltage and initial dimethylamine (DML) concentration are important factors that influence the DML removal efficiency and energy yield. The conversion of DML of 761mg/m³ reaches 100% at a peak voltage of 41.25kV. Under the experiment conditions, the conversion of DML increases with an increase of oxygen contents. And the highest DML conversion was achieved with the gas stream containing 0.3% water. Simultaneously, the concentration of O₃ and OH radical in reactor was measured. Higher conversion, higher energy yield and fewer byproducts were found in mixed odor (DML+dimethyl sulfide (DMS)) treatment than that in single odor treatment. The energy yield is promoted from 2.13 to 5.20mg/kJ.