Acoustic droplet vaporization for enhancement of thermal ablation by high intensity focused ultrasound

M Zhang, ML Fabiilli, KJ Haworth, F Padilla… - Academic radiology, 2011 - Elsevier
RATIONALE AND OBJECTIVES: Acoustic droplet vaporization (ADV) shows promise for
spatial control and acceleration of thermal lesion production. The investigators hypothesized
that microbubbles generated by ADV could enhance high-intensity focused ultrasound
(HIFU) thermal ablation by controlling and increasing local energy absorption. MATERIALS
AND METHODS: Thermal lesions were produced in tissue-mimicking phantoms using
focused ultrasound (1.44 MHz) with a focal intensity of 4000 W· cm− 2 in degassed water at …
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