[PDF][PDF] Active surveillance can reduce overtreatment in patients with low-risk prostate cancer.

FB Thomsen, MA Røder, H Hvarness… - …, 2013 - content.ugeskriftet.dk
Histopathology, 2013content.ugeskriftet.dk
Dan Med J 2013; 60 (2): A4575 2 danish mEdical JOURnal Dan Med J 60/2 February 2013
diagnosed after transurethral prostatectomy were included following re-biopsy, and the post-
transurethral prostatectomy PSA-value was used as entry PSA. Patients were followed with
digital rectal examination and PSA-tests every three months; and re-biopsies were offered
after one year on active surveillance. The risk of progression was hereafter classified
according to a modification of criteria originally proposed by Choo et al [10] and patients …
Dan Med J 2013; 60 (2): A4575
2 danish mEdical JOURnal Dan Med J 60/2 February 2013 diagnosed after transurethral prostatectomy were included following re-biopsy, and the post-transurethral prostatectomy PSA-value was used as entry PSA. Patients were followed with digital rectal examination and PSA-tests every three months; and re-biopsies were offered after one year on active surveillance. The risk of progression was hereafter classified according to a modification of criteria originally proposed by Choo et al [10] and patients were managed as outlined in Table 1.
The PSA doubling time was calculated according to the Memorial Sloan-Kettering Cancer Center guidelines including all available PSA-values. Kaplan-Meier survival analysis was used to estimate the probability of remaining on active surveillance. Data are presented as median and range unless otherwise in-
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