… Thus, albumin may have specific functions during infection. Here, we describe the ability of
albumin to neutralize hydrophobic microbial toxins. We show that albumin can protect against …

… Candida albicans is the major cause of VVC, but the incidence of infections caused by
non-albicans Candida … peptides, which can modulate its growth and pathogenic potential. The …

… Candida albicans is an opportunistic pathogen and colonizer … . found that albumin neutralized
hydrophobic microbial toxins, … new roles for albumin in modulating farnesol secretion by C. …

… involves neutralization of the toxin by albumin, which acts as an anti-toxin through hydrophobic
… This effect is mediated via modulation of the mitogen activated kinase Mck1, the stress …

… Candidalysin, however, acts as a peptide toxin to induce … Of note, albumin as an abundant
protein in human serum … (Sap9 and Sap10), biofilm modulation (Sap8-Sap10), host immune …

… owing to the amphipathic and hydrophobic features of the … ), the neutralization of candidalysin
or modulation of downstream … may neutralize the biological activity of the toxin and thereby …

… toxins produced by bacteria, fungi, and insects. This led to the discovery of a vital biological,
… Our research therefore shows that albumin inhibits C. … modulates C.albicans pathogenicity …

… Candidalysin is a 31-amino-acid peptide toxin with amphipathic … albumin has been shown
to neutralize candidalysin via a hydrophobic interaction, reducing the pathogenicity of C. …

… -bCts) had a synergistic effect against Candida albicans especially at low concentrations of
BSA… A recent study even reported that albumin could modulate C. albicans pathogenicity [30], …

… as against Candida albicans infection by inactivating toxins … (GEM) in complex with albumin.
GEM is an orally administered lipid… Of note, the catalytic properties of HSA are modulated by …