Alignment of whole genomes

AL Delcher, S Kasif, RD Fleischmann… - Nucleic acids …, 1999 - academic.oup.com
… Gaps in the MUM alignment can be also caused by sequences that have large numbers
of differences, but that still should be aligned in the whole genome alignment. Because the …

Whole-genome alignment and comparative annotation

J Armstrong, IT Fiddes, M Diekhans… - Annual review of …, 2019 - annualreviews.org
… For our purposes in this article, we call any alignment that allows rearrangements (ie, does
whole-genome alignment (or for short, a genome alignment). Most whole-genome alignment

Mugsy: fast multiple alignment of closely related whole genomes

SV Angiuoli, SL Salzberg - Bioinformatics, 2011 - academic.oup.com
… -genomes, and genome evolution. Results: We present a new multiple alignment tool for
whole genomes … efficient and can align 31 Streptococcus pneumoniae genomes in less than 2 …

Alignathon: a competitive assessment of whole-genome alignment methods

D Earl, N Nguyen, G Hickey, RS Harris… - Genome …, 2014 - genome.cshlp.org
… in the more general problem of whole-genome alignment (WGA). Using the same … genomes.
In total, 35 submissions were assessed, submitted by 10 teams using 12 different alignment

Strategies and tools for whole-genome alignments

O Couronne, A Poliakov, N Bray, T Ishkhanov… - Genome …, 2003 - genome.cshlp.org
… As we mentioned above, an alignment of the whole human and mouse genomes represents
an algorithmic challenge and yet holds the promise of significant biological understanding. …

Whole-genome alignment

CN Dewey - Evolutionary Genomics: Statistical and Computational …, 2012 - Springer
whole-genome aligners and offer a set of methodological challenges that need to be tackled
in order to make the most effective use of our rapidly growing databases of whole genomes. …

New whole-genome alignment tools are needed for tapping into plant diversity

B Song, ES Buckler, MC Stitzer - Trends in Plant Science, 2024 - cell.com
… because of frequent whole-genome duplications (WGDs) as … classical pairwise and multiple
genome alignment (MGA) … genome alignment and the interpretation of alignment results …

Whole-genome alignment

CN Dewey - Evolutionary genomics: Statistical and computational …, 2019 - Springer
whole-genome aligners and offer a set of methodological challenges that need to be tackled
in order to make most effective use of our rapidly growing databases of whole genomes. …

Automated whole-genome multiple alignment of rat, mouse, and human

M Brudno, A Poliakov, A Salamov, GM Cooper… - Genome …, 2004 - genome.cshlp.org
… a whole-genome multiple alignment of the three currently available mammalian genomes
… Berkeley Genome Pipeline and the LAGAN program. The strategy is based on progressive …

Evolution at the nucleotide level: the problem of multiple whole-genome alignment

CN Dewey, L Pachter - Human molecular genetics, 2006 - academic.oup.com
… to frame our discussion of alignment methods. After reviewing the latest in alignment
technology, we discuss methods that utilize whole-genome alignments for biological discovery. …