Altered cross-frequency coupling in resting-state MEG after mild traumatic brain injury

M Antonakakis, SI Dimitriadis, M Zervakis… - International Journal of …, 2016 - Elsevier
Cross-frequency coupling (CFC) is thought to represent a basic mechanism of functional
integration of neural networks across distant brain regions. In this study, we analyzed CFC
profiles from resting state Magnetoencephalographic (MEG) recordings obtained from 30
mild traumatic brain injury (mTBI) patients and 50 controls. We used mutual information (MI)
to quantify the phase-to-amplitude coupling (PAC) of activity among the recording sensors in
six nonoverlapping frequency bands. After forming the CFC-based functional connectivity …
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