Altered lipidome and antioxidative activity of small, dense HDL in normolipidemic rheumatoid arthritis: relevance of inflammation
LG Rosso, M Lhomme, T Merono, P Sorroche… - Atherosclerosis, 2014 - Elsevier
Objective: High-density lipoprotein (HDL) particles exert potent antiatherogenic activities,
including antioxidative actions, which are relevant to attenuation of atherosclerosis
progression. Such activities are enriched in small, dense HDL and can be compromised
under conditions of chronic inflammation like rheumatoid arthritis (RA). However, structure–
function relationships of HDL largely remain indeterminate. Methods: The relationships
between HDL structure and function were evaluated in normolipidemic patients with active …
including antioxidative actions, which are relevant to attenuation of atherosclerosis
progression. Such activities are enriched in small, dense HDL and can be compromised
under conditions of chronic inflammation like rheumatoid arthritis (RA). However, structure–
function relationships of HDL largely remain indeterminate. Methods: The relationships
between HDL structure and function were evaluated in normolipidemic patients with active …
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