Background Treatment of parasitic diseases has been challenging due to evolution of drug
resistant parasites, and thus there is need to identify new class of drugs and drug targets.
Protein translation is important for survival of malarial parasite, Plasmodium, and the
pathway is present in all of its life cycle stages. Aminoacyl tRNA synthetases are primary
enzymes in protein translation as they catalyse amino acid addition to the cognate tRNA.
This study sought to understand differences between Plasmodium and human aminoacyl …

Abstract Treatment of parasitic diseases has been challenging due to the development of
drug resistance by parasites, and thus there is need to identify new class of drugs and drug
targets. Protein translation is important for survival of plasmodium and the pathway is
present in all the life cycle stages of the plasmodium parasite. Aminoacyl tRNA synthetases
are primary enzymes in protein translation as they catalyse the first reaction where an amino
acid is added to the cognate tRNA. Currently, there is limited research on comparative …