… Therefore, in this study we aimed to investigate the association between amiodarone and the
risk of stroke among a nationwide population-based cohort of 7548 patients with nonvalvular AF.
… As not all patients received amiodarone during the study period, we used a Cox proportional
hazard model with time-dependent exposure covariates to reduce the bias resulting from
overestimation of the effect of amiodarone on ischemic stroke risk. Model 1 controlled for
age, sex, ischemic heart disease, diabetes, hypertension, heart failure, hyperlipidemia, … In …