Fucose is an important component of many oligo-and polysaccharide structures as well as
glycoproteins and glycolipids, which are often associated with a variety of physiological
processes ranging from fertilization, embryogenesis, signal transduction, and disease
progression, such as rheumatoid arthritis, inflammation, and cancer. The enzyme α-l-
fucosidase is involved in the cleavage of the fucosidic bond in glycans and glycoconjugates,
particularly the Fuc-α-1, 2-Gal, Fuc-α-1, 3/4-GlcNAc, and Fuc-α-1, 6-GlcNAc linkages. Here …