… Most importantly, this review emphasizes a critical role for animal research in understanding
… of drug addiction. Drug addiction is a lay term that refers to maladaptive drug use and an …

… modeling of human drug addiction in laboratory animals. The … used animal species in
experimental addiction research (see … drugs of abuse, routes of self-administration and animal …

… models of different stages of the addiction cycle. 1, 3 For the present chapter, the animal
models are organized by the stage of the addiction … being used for an animal model may or may …

… The study of drug addiction integrates research from a wide range … animals have been a
critical part of this endeavour for close to 100 years. The rise of animal models in drug addiction …

… drug. Fourth, evaluations of potential pharmacotherapies for drug addiction in animal models
… Predictive validity of those models would actually improve if they were to adopt protocols …

… power of preclinical animal models. Here, I argue that animal models of voluntary drug
intake—under nonoperant and operant conditions—and addiction models based on the …

… Thus, the two models independently capture two different phases of addiction. Next, we
discuss behavioral addictions that share several similarities with drug addiction, with an …

… In spite of the availability of a seemingly excellent animal model, drug addiction remains …
such a well developed animal model and so little success in treating addiction? Is the model …

… of an animal model An animal model is a preparation in one organism that allows for the
study of one or several aspects of a human condition. Thus a model of drug addiction must …

… vide addiction researchers with an animal model of relapse, the ‘‘reinstatement’’ model of drug
self-… Many preclinical animal models of relevance to human drug addiction exist, including …