Antibody responses to SARS-CoV-2 vaccines in 45,965 adults from the general population of the United Kingdom
We report that in a cohort of 45,965 adults, who were receiving either the ChAdOx1 or the
BNT162b2 SARS-CoV-2 vaccines, in those who had no prior infection with SARS-CoV-2,
seroconversion rates and quantitative antibody levels after a single dose were lower in older
individuals, especially in those aged> 60 years. Two vaccine doses achieved high
responses across all ages. Antibody levels increased more slowly and to lower levels with a
single dose of ChAdOx1 compared with a single dose of BNT162b2, but waned following a …
BNT162b2 SARS-CoV-2 vaccines, in those who had no prior infection with SARS-CoV-2,
seroconversion rates and quantitative antibody levels after a single dose were lower in older
individuals, especially in those aged> 60 years. Two vaccine doses achieved high
responses across all ages. Antibody levels increased more slowly and to lower levels with a
single dose of ChAdOx1 compared with a single dose of BNT162b2, but waned following a …
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