Antimicrobial peptides: clinical relevance and therapeutic implications

FP da Silva, MCC Machado - Peptides, 2012 - Elsevier
Antimicrobial peptides (AMPs) are molecules that provide protection against environmental
pathogens, acting against a large number of microorganisms, including bacteria, fungi,
yeast, virus and others. Two major groups of antimicrobial peptides are found in humans:
cathelicidins and defensins. Recently, several studies have furnished information that
besides their role in infection diseases, antimicrobial peptides play a role in diseases as
diverse as inflammatory disorders, autoimmunity and cancer. Here, we discuss the role of …
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