Antimicrobial peptides for leishmaniasis

SL Cobb, PW Denny - Current opinion in …, 2010 - durham-repository.worktribe.com
… against drug-resistant strains of Leishmania. This review summarizes research aimed at
investigating the potential development of antimicrobial peptide-based antileishmanial agents. …

Modes of action of Leishmanicidal antimicrobial peptides

AK Marr, BS McGwire, WR McMaster - Future microbiology, 2012 - Taylor & Francis
… The modes of action of these peptides against Leishmania includes: membrane disruption
… This article reviews the mechanisms of action of antimicrobial peptides with leishmanicidal …

Interactions of antimicrobial peptides with Leishmania and trypanosomes and their functional role in host parasitism

BS McGwire, MM Kulkarni - Experimental parasitology, 2010 - Elsevier
Antimicrobial peptides (AMPs) are multifunctional components of the innate systems of
both insect and mammalian hosts of the pathogenic trypanosomatids Leishmania and …

Induction of autophagic cell death in Leishmania donovani by antimicrobial peptides

A Bera, S Singh, R Nagaraj, T Vaidya - Molecular and biochemical …, 2003 - Elsevier
… We demonstrate that antimicrobial peptides induce an autophagic cell death in the … ,
Leishmania donovani. In our study, three antimicrobial peptides, Indolicidin, and two peptides

Temporins, small antimicrobial peptides with leishmanicidal activity

ML Mangoni, JM Saugar, M Dellisanti, D Barra… - Journal of Biological …, 2005 - ASBMB
… Gene-encoded antimicrobial peptides are promising candidates, but so … antimicrobial
peptides secreted from the skin of the European red frog Rana temporaria, display anti-Leishmania

Safety and efficacy of antimicrobial peptides against naturally acquired leishmaniasis

J Alberola, A Rodriguez, O Francino… - Antimicrobial agents …, 2004 - Am Soc Microbiol
Antimicrobial peptides are rarely used as alternative treatments for … antimicrobial peptide
Oct-CA(1-7)M(2-9) is safe and effective for treating naturally acquired canine leishmaniasis. …

Comparative study of different forms of Jellein antimicrobial peptide on Leishmania parasite

F Zahedifard, H Lee, JH No, M Salimi, N Seyed… - Experimental …, 2020 - Elsevier
… increasing its stability may improve the antimicrobial effect. The results of this study revealed
that potentiating antimicrobial activity of the peptides with different modification is strongly …

Leishmania donovani: thionins, plant antimicrobial peptides with leishmanicidal activity

M Berrocal-Lobo, A Molina… - Experimental …, 2009 - Elsevier
… plant antibiotic peptides (PAPs) from the principal families, such wheat thionins, a barley
lipid transfer protein and potato defensins and snakins were tested in vitro against Leishmania

Peptides to tackle leishmaniasis: Current status and future directions

AA Robles-Loaiza, EA Pinos-Tamayo… - International journal of …, 2021 - mdpi.com
… been proposed as underlying the action of peptides against Leishmania parasites, but they
are mostly based on what is known about antimicrobial peptides in general, and hence lack …

Activity of Anti-Microbial Peptides (AMPs) against Leishmania and Other Parasites: An Overview

R El-Dirany, H Shahrour, Z Dirany, F Abdel-Sater… - Biomolecules, 2021 - mdpi.com
… -leishmanial activity of many AMPs families has only been studied in recent years. Leishmaniasis,
a parasitic illness caused by LeishmaniaLeishmaniasis is considered by WHO as a …