Apoptosis in virus infection dynamics models

R Fan, Y Dong, G Huang, Y Takeuchi - Journal of biological …, 2014 - Taylor & Francis
In this paper, on the basis of the simplified two-dimensional virus infection dynamics model,
we propose two extended models that aim at incorporating the influence of activation-
induced apoptosis which directly affects the population of uninfected cells. The theoretical
analysis shows that increasing apoptosis plays a positive role in control of virus infection.
However, after being included the third population of cytotoxic T lymphocytes immune
response in HIV-infected patients, it shows that depending on intensity of the apoptosis of …

Apoptosis in virus infection dynamics models.

FRL Fan RuiLi, DYP Dong YuePing, HG Huang Gang… - 2014 - cabidigitallibrary.org
In this paper, on the basis of the simplified two-dimensional virus infection dynamics model,
we propose two extended models that aim at incorporating the influence of activation-
induced apoptosis which directly affects the population of uninfected cells. The theoretical
analysis shows that increasing apoptosis plays a positive role in control of virus infection.
However, after being included the third population of cytotoxic T lymphocytes immune
response in HIV-infected patients, it shows that depending on intensity of the apoptosis of …
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