Since gastrointestinal mucosa is constantly exposed to reactive oxygen species from various
sources, the presence of antioxidants may contribute to the body's natural defenses against
inflammatory diseases. Hypothesis To define the polyphenols extracted from dried apple
peels (DAPP) and determine their antioxidant and anti-inflammatory potential in the
intestine. Caco-2/15 cells were used to study the role of DAPP preventive actions against
oxidative stress (OxS) and inflammation induced by iron-ascorbate (Fe/Asc) and …

The corresponding author stated that the similarities between reference (housekeeping)
protein blots are due to the stripping and re-probing of the same blot, and commented that
some blot images were spliced to remove extra lanes and/or duplicate or triplicate samples
from the panel. The corresponding author provided image data to support the results
presented in Figs 8A, 8B and 9A. The underlying data for Fig 8B confirm that the panel has
been spliced, but the underlying data provided for Fig 8A and Fig 9A do not appear to match …