Application of antimicrobial polypeptide host defenses to aquaculture: Exploitation of downregulation and upregulation responses

EJ Noga, AJ Ullal, J Corrales… - … and Physiology Part D …, 2011 - Elsevier
Antimicrobial polypeptides (AMPPs), consisting of peptides and small proteins with
antimicrobial activity, are an integral component of innate immunity. Their often potent
properties and widespread prevalence in fish suggests that designing means of
manipulating their levels has considerable potential for maintaining or improving fish health.
There is evidence that a number of chronic stresses lead to significant downregulation of
AMPPs and thus their monitoring could be a highly sensitive measure of health status and …
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