Assessment of an Association between an Aryl Hydrocarbon Receptor Gene (AHR) Polymorphism and Risk of Male Infertility
A Gu, G Ji, Y Long, Y Zhou, X Shi, L Song… - Toxicological …, 2011 - academic.oup.com
The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor that mediates
the toxicity of a variety of environmental chemicals, such as polycyclic aromatic
hydrocarbons (PAHs) and dioxins. We hypothesized that polymorphisms of AHR may result
in significant differences in sensitivity to toxic effects of PAHs or dioxins and contribute to
susceptibility to male infertility. To address this possibility, we conducted a study including
580 idiopathic infertile subjects and 580 fertile controls to assess associations between the …
the toxicity of a variety of environmental chemicals, such as polycyclic aromatic
hydrocarbons (PAHs) and dioxins. We hypothesized that polymorphisms of AHR may result
in significant differences in sensitivity to toxic effects of PAHs or dioxins and contribute to
susceptibility to male infertility. To address this possibility, we conducted a study including
580 idiopathic infertile subjects and 580 fertile controls to assess associations between the …
Assessment of an association between an aryl hydrocarbon receptor gene (AHR) polymorphism and risk of male infertility.
GAH Gu AiHua, JGX Ji GuiXiang, LY Long Yan, Y Zhou… - 2011 - cabidigitallibrary.org
The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor that mediates
the toxicity of a variety of environmental chemicals, such as polycyclic aromatic
hydrocarbons (PAHs) and dioxins. We hypothesized that polymorphisms of AHR may result
in significant differences in sensitivity to toxic effects of PAHs or dioxins and contribute to
susceptibility to male infertility. To address this possibility, we conducted a study including
580 idiopathic infertile subjects and 580 fertile controls to assess associations between the …
the toxicity of a variety of environmental chemicals, such as polycyclic aromatic
hydrocarbons (PAHs) and dioxins. We hypothesized that polymorphisms of AHR may result
in significant differences in sensitivity to toxic effects of PAHs or dioxins and contribute to
susceptibility to male infertility. To address this possibility, we conducted a study including
580 idiopathic infertile subjects and 580 fertile controls to assess associations between the …
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