Biomedical wastes generated in hospitals and clinics and its management is becoming an area of great concern and importance in view of potential public health risks associated with such wastes. Biomedical waste management is complex issue as it has several dimension associated with it like proper and safe disposal of waste, waste treatment technologies and development of environmental friendly treatment and management technologies. In many developing countries like India, the insufficiency of data regarding the composition and quantity of biomedical waste is one of the considerable reasons for inappropriate biomedical waste management. This study explores the present scenario of biomedical waste management, handling, practices, generation, and treatment of biomedical waste management within Rishikesh region (part of Uttarakhand, India). The biomedical waste related practices have been studied at three major hospitals of Rishikesh which includes AIIMS (All India Institute of Medical Sciences), Government hospital and NAH (Nirmal ashram hospital)(private) starting from month of October 2017 to February 2018 by analyzing the procurement lists. The data is analyzed to find variation in biomedical waste generation over the study period. The average waste generated per day (kg/day) in AIIMS, Government hospital, NAH was 286.64, 123.263, and 63.653. Whereas average number of patients/day were 1314.88, 360.42, and 120.1 along with the total bed capacity of 439,165, and 130 respectively in each hospitals. The cross-sectional study involves various issues like sources, container and color coding types, qualitative and quantitative composition of infectious wastes along with different methods of waste handling, collection, segregation, treatment and disposal methods. After investigating all aspects, it was founded that there is lack of proper disposal methods in the government hospital and NAH as compared with the AIIMS, although waste is transported from all the three hospitals to the same combined biomedical waste treatment plant (CBMWTP) for disposal. This study will help in tackling these emerging issues related to biomedical waste management.