Myoblast transplantation is a potential therapy for severe muscle trauma, myopathies and
heart infarct. Success with this therapy relies on the ability to obtain cell preparations
enriched in myogenic precursor cells and on their survival after transplantation. To define
myoblast transplantation strategies applicable to patients, we used a large animal model,
the pig. Muscle dissociation procedures adapted to porcine tissue gave high yields of cells
containing at least 80% myogenic precursor cells. Autologous transplantation of 3 [H] …