… autophagy and lysosomes in stress response and longevity. We highlight the connections
between autophagy … links between autophagic dysfunction, neurodegenerative diseases, and …

… indicates that autophagy plays a key role in aging and aging-related diseases. Enhanced
autophagy can delay aging and prolong life span. The absence of autophagy leads to the …

… autophagy lead to accelerated aging? In which cases does increased autophagy counteract
normal or pathological aging … link autophagy, cytoprotection, longevity, and healthy aging? …

… that autophagy has a crucial role in the regulation of animal lifespan. Basal level of autophagic
activity is elevated in many longevity … In most cases, genes involved in autophagy and …

… numerous autophagy-related genes or proteins are directly regulated by longevity pathways.
… that autophagy is a central regulatory mechanism for aging in diverse eukaryotic species. …

… autophagy led to a delayed onset of aging. A study done on human diploid fibroblasts suggests
that some autophagy … levels of autophagy in the nervous system enhances longevity and …

… contributes to development of age-related diseases, for instance, … of the autophagy pathways,
and thus the discussion on the roles of these autophagy pathways on development of age-…

… longevity require autophagy. Interestingly, the recently gained knowledge about … autophagy
proteins has emerged as an essential regulatory mechanism of both autophagy and longevity…

… basal autophagy showed extended longevity and reduced age-related phenotypes. Autophagy
promotes longevity … of defective mitochondria that accumulate during aging. In principle, …

… concepts relevant to autophagy and its role in modulating longevity have emerged. …
autophagy activation in longevity paradigms, as tissue-specific overexpression of single autophagy …