[HTML][HTML] Autophagy-induced mesenchymal stem cell-derived extracellular vesicles ameliorated renal fibrosis in an in vitro model

B Ahrabi, HA Abbaszadeh, A Piryaei, F Shekari… - BioImpacts …, 2023 - ncbi.nlm.nih.gov
B Ahrabi, HA Abbaszadeh, A Piryaei, F Shekari, NA Roozbahany, M Rouhollahi…
BioImpacts: BI, 2023ncbi.nlm.nih.gov
… Chronic and progressive damage to the kidney by inflammatory processes, may lead to
an increase in the extracellular matrix production, a condition known as renal fibrosis. The
current study aims to evaluate if the extracellular vesicles (EVs) derived from autophagic
adipose-derived mesenchymal stem cells (ADMSCs) can reduce the inflammation and
extracellular matrix accumulation in damaged kidney tissue. … In this study, by using
curcumin, autophagy was induced in adipose-derived mesenchymal stem cells (ADMSCs) …
Abstract
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ncbi.nlm.nih.gov
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