Melanogenesis is the process of production of melanin pigments that are responsible for the
colors of skin, eye, and hair and provide protection from ultraviolet radiation. However,
excessive levels of melanin formation cause hyperpigmentation disorders such as freckles,
melasma, and age spots. Liver X receptors (LXR) are nuclear oxysterol receptors belonging
to the family of ligand-activated transcription factors and physiological regulators of lipid and
cholesterol metabolism. In the skin, activation of LXRs stimulates differentiation of …

Melanogenesis is the process of production of melanin pigments that are responsible for the
colors of skin, eye, and hair and provide protection from ultraviolet radiation. However,
excessive levels of melanin formation cause hyperpigmentation disorders such as freckles,
melasma, and age spots. Liver X receptors (LXR) are nuclear oxysterol receptors belonging
to the family of ligand-activated transcription factors and physiological regulators of lipid and
cholesterol metabolism. In the skin, activation of LXRs stimulates differentiation of …