Obesity is the fastest-growing cause of disease and death in the United States, with minority populations suffering some of the most severe consequences. Latinos constitute 16% of the U.S. population as of 2010, and have a higher proportion of the population that is overweight and obese compared with their non-Hispanic Black and White counterparts. Although there are over 15.8 million Latino residents living in non-gateway states (outside California, Texas, Arizona, Illinois, and New York), there is little research exploring obesity factors among Latinos outside of gateway states. The aim of this paper was to study socio-economic characteristics, mental health, insurance status, physical activity, and fruit and vegetable consumption, in relation to body mass index (BMI) among Latinos living in a non-gateway state. The results showed that income, employment status, marital status, insurance status, physical activity, fruit and vegetable consumption, and mental health were all associated with BMI.