Objective Unequivocal modulation of glycemic homeostasis by chronic beta-adrenergic
blockade in diabetes has never been demonstrated. This study investigates the participation
of beta-adrenergic system in glycemic control and muscle glucose transporter GLUT4
expression in insulin-treated diabetic rats. Methods Insulin-treated diabetic Wistar (W) or
spontaneously hypertensive rats (SHR) were additionally treated with propranolol, and
glycemic homeostasis and expression of some target mRNAs and proteins in soleus and …