When characterizing biomolecular interactions, avidity, is an umbrella term used to describe
the accumulated strength of multiple specific and unspecific interactions between two or
more interaction partners. In contrast to the affinity, which is often sufficient to describe
monovalent interactions in solution and where the binding strength can be accurately
determined by considering only the relationship between the microscopic association and
dissociation rates, the avidity is a phenomenological macroscopic parameter linked to …