Bioactive oligopeptides in dermatology: Part II

BY Reddy, T Jow, BM Hantash - Experimental dermatology, 2012 - Wiley Online Library
Peptides are central to the regulation and modulation of the chemical reactions and
biological responses that occur in nature. Many physiological processes are affected by the
interactions of these peptides, including cell proliferation and migration, inflammation,
melanogenesis, angiogenesis and innate immunity. Thus, biologically active peptides offer a
great potential medically and therapeutically. Moreover, the ability to generate synthetic
peptides with attention to specifically modulating their pharmacokinetics and properties for …

Bioactive oligopeptides in dermatology: Part I

B Reddy, T Jow, BM Hantash - Experimental dermatology, 2012 - Wiley Online Library
Short sequence amino acids or oligopeptides represent a relatively new and promising area
of dermatology. Oligopeptides are defined as peptide sequences ranging from 2 to 20 amino
acids. This class of proteins includes potent biologically active compounds, which can
modulate various cellular and molecular processes. The medical potential of short sequence
peptides was initially characterized many decades ago with the identification of biological
mediators such as angiotensin, vasopressin, oxytocin and bradykinin. However, the role of …
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