Bioinspired vascular stents with microfluidic electrospun multilayer coatings for preventing in‐stent restenosis
Y Cheng, X Zhang, R Liu, Y Li, J Zeng… - Advanced …, 2022 - Wiley Online Library
In‐stent restenosis (ISR) is seriously affecting the long‐term prognosis of vascular
interventional therapy and leading to enormous medical burdens. Great efforts have been
devoted to developing functional vascular stents with desired features and properties for
effective ISR prevention. Here, a multifunctional bionic vascular stent with designed coatings
prepared using microfluidic electrospinning technology is presented. Such stents are
composed of biocompatible, drug‐loaded methylacrylated gelatin‐polyethylene glycol …
interventional therapy and leading to enormous medical burdens. Great efforts have been
devoted to developing functional vascular stents with desired features and properties for
effective ISR prevention. Here, a multifunctional bionic vascular stent with designed coatings
prepared using microfluidic electrospinning technology is presented. Such stents are
composed of biocompatible, drug‐loaded methylacrylated gelatin‐polyethylene glycol …
Bioinspired Vascular Stents with Microfluidic Electrospun Multilayer Coatings for Preventing In‐Stent Restenosis (Adv. Healthcare Mater. 17/2022)
Y Cheng, X Zhang, R Liu, Y Li, J Zeng… - Advanced …, 2022 - Wiley Online Library
As shown in the cover picture, the bionic vascular stent prepared by Min Zhou, Yuanjin
Zhao, and co-workers in article 2200965, is covered with double-layer nanofiber
membranes made by electrospinning technology. The inner layer is loaded with Heparin-
VEGF (shown in yellow spheres), which can be released into the lumen and promote
endothelial repair. The outer membrane is loaded with rapamycin (shown in blue triangles),
which can be released into the walls of blood vessels and prevents proliferation of vascular …
Zhao, and co-workers in article 2200965, is covered with double-layer nanofiber
membranes made by electrospinning technology. The inner layer is loaded with Heparin-
VEGF (shown in yellow spheres), which can be released into the lumen and promote
endothelial repair. The outer membrane is loaded with rapamycin (shown in blue triangles),
which can be released into the walls of blood vessels and prevents proliferation of vascular …
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